Juliette AzimzadehChercheuse CNRS à l'Institut Jacques Monod (IJM) - ( CNRS / Université de Paris )

Mes recherches

A cell biologist by training, I have been fascinated by the microtubule cytoskeleton and its role in cell growth and morphogenesis since the beginning of my career. I performed my doctoral work at the Institut Jean-Pierre Bourgin in Versailles to study the role of microtubules in plant morphogenesis, and then joined the group of Michel Bornens at the Institut Curie in Paris, where I focused on molecular mechanisms underlying centriole assembly in human cells. After this, I joined the laboratory of Wallace Marshall at the University of California in San Francisco, where I established the freshwater planarian, a flatworm best known for its remarkable ability to regeneration, as a model system to study centriole assembly and ciliogenesis. I established my own group in 2013 at the Institut Jacques Monod in Paris. My current research goals combine approaches from cell, developmental and evolutionary biology to address the mechanisms that control the assembly and positioning of centrioles in animal cells. For this, we use both mammalian culture cells and planarians. We are in particular interested in the polarization of multi-ciliated epithelia and the molecular origin of centriole structural asymmetry.