Multiple functions of RNA in gene regulation

20 novembre 2018

Roscoff (Brittany), France - May 3-7, 2006

Chairperson: Pascale ROMBY

UPR 9002 C.N.R.S.

Institut de Biologie Moléculaire et Cellulaire

15, rue René Descartes

F-67084 STRASBOURG CEDEX France

Phone: +33 3 88 41 70 51 Fax: +33 3 88 60 22 18

E-mail: P.Romby@ibmc.u-strasbg.fr

Vice-Chairperson: E. Gerhart H. WAGNER

Department of Cell and Molecular Biology - Microbiology Program

Biomedical Center

Uppsala University

Box 596

S-751 24 UPPSALA Sweden

Phone: +46 18 4714866 Fax: +46 18 530396

E-mail: gerhart.wagner@icm.uu.se

RNA molecules are now recognized as central and key effectors in the regulation of gene expression. This meeting will bring together scientists of various disciplines working on a wide range of regulatory RNAs. The discoveries of non-coding RNAs, microRNAs and silencing RNAs in eukaryotes as well as of small RNAs and riboswitches elements in prokaryotes have transformed our views on gene regulation and expression. In recent years, gene expression processes have also been studied in a global perspective. Studies of messenger-ribonucleoprotein (mRNP) components and dynamics suggests that mRNPs organize and regulate subpopulations of functionally related mRNAs. This conference will provide opportunities to report on and compare new features that have emerged on RNA-dependent regulatory networks in eukaryotes - animals and plants -, as well as in prokaryotes. The following topics will be covered:

RNA in epigenetic control
Regulatory RNAs in eukaryotes
Regulatory RNAs in bacteria
Regulatory elements in mRNA
mRNP in post-transcription control

Invited speakers

(Provisional titles or presentations)

AKOULITCHEV Alexandre (Oxford, UK) Non-coding RNA in transcription: from initiation to termination

AMBROS Victor (Hannover, USA) MicroRNAs and the control of animal development

BARLOW Denise (Vienna, Austria) Non-coding RNAs silence imprinted genes

BASS Brenda (Salt Lake City, USA) dsRNA binding proteins in RNA editing and RNA interference

BASSLER Bonnie (Princeton, USA) Cell to cell communication in bacteria : small RNA control of quorum sensing

BAULCOMBE David (Norwich, UK) Post-transcriptional silencing in plants

BENSAUDE Olivier (Paris, France) 7SK RNA regulates the activity of the positive transcription elongation factor

BERTRAND Edouard (Montpellier, France) Intra-cellular traffic of C/D snoRNPs

BRANLANT Christiane (Nancy, France) Novel snoRNAs in archeabacteria

BREAKER Ron (New Haven, USA) Genetic control by riboswitches

CAVAILLE Jérôme (Toulouse, France) Imprinted small RNA genes in the human 15q11q13 and 14q32 domain

COSSART Pascale (Paris, France) RNA-dependent regulation of virulence gene expression in L. monocytogenes

EHRENBERG Mans (Uppsala, Sweden) Accuracy of initiation of mRNA translation

EKWALL Karl (Huddinge, Sweden) RNA polymerase II is required for RNAi-directed chromatin silencing

EPHRUSSI Anne (Heidelberg, Germany) Assembly of the oskar mRNA localization-translation complex

FILIPOWICZ Witold (Basel, Switzerland) RISC machinery can be used to direct inhibition of translation via either miRNA or regulatory proteins

FUJIYUKI Tomoko (Tokyo, Japan) Kaguko virus : a novel RNA virus identified in the brains of aggressive worker honeybees

HAMMOND Scott (Chapel Hill, USA) RNAi, microRNAs, and human disease

IZAURRALDE Elisa (Heidelberg, Germany) mRNA surveillance : molecular mechanisms and interaction networks

KEENE Jack D (Durham, USA) RNA based operons and regulons

NELLEN Wolfgang (Kassel, Germany) Comparison between RNAi and antisense mediated RNA silencing in Dictyostelium

OSBORNE Howard Beverley (Rennes, France) Post-transcriptional regulation by EDEN-BP in Xenopus laevis and mouse embryos

PRATS Anne-Catherine (Toulouse, France) IRES-dependent translational control of gene expression

ROMBY Pascale (Strasbourg, France) Regulatory RNAIII and virulence in S. aureus

SPRINGER Mathias (Paris, France) Protein mediated translational control in Escherichia coli: the recognition of a large operator by a small repressor

VOINNET Olivier (Strasbourg, France) Viral suppression of RNAi, plant miRNA, relationship between miRNAs and oncogenesis

WAGNER Gerhart H. (Uppsala, Sweden) Bacterial regulatory RNAs

WESTHOF Eric (Strasbourg, France) Evolution of RNA architecture

YAO Meng-Chao (Taipei, Taiwan) RNA-guided DNA deletion in Tetrahymena

Deadline for application: february 8, 2006

Registration fee (including board and lodging):

350 € for PhD students
550 € for other participants

Application for registration

The total number of participants is limited to about 100 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should send:

their curriculum vitae
the list of their main publications for the 3 last years
the abstract of their presentation

to the chairman of the conference before the deadline. After it, the chairman will select the participants. Except in some particular cases approved by the chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.